No single best amplifier here. What decides it is what you have to drive, what you need to plug in, and how much of the system you want in one box.
| Area | Better | Why |
|---|
| Power | evenly matched | Effectively the same output - 60W against 60W into 8 ohms is under 1dB, which is not an audible difference in loudness. |
| Grip on hard loads | B | OSD Nero Stream XD2 holds up better into a 4-ohm load: its output nearly doubles to 120W, where the other barely increases. That matters with demanding speakers far more than the 8-ohm figure does. |
| Noise floor | A | Yamaha A-S301 is the quieter design on paper - 99dB against 95dB. Audible mainly with sensitive speakers in a quiet room. |
| Built-in DAC | evenly matched | Both have a DAC on board with much the same capability. |
| Analogue inputs | A | Yamaha A-S301 takes more analogue sources - 6 against 1. |
| Phono stage | depends | Yamaha A-S301 has a built-in phono stage (MM) and OSD Nero Stream XD2 does not. Decisive if you own a turntable, completely irrelevant if you do not - and an outboard phono stage is easy to add later either way. |
| Room to grow | evenly matched | The same expansion options on both. |
| Amplifier class | depends | Yamaha A-S301 is Class A/B and OSD Nero Stream XD2 is Class D. Class A/B runs warm and is the long-established mainstream choice; Class D runs cool and draws almost nothing at idle. Modern examples of both measure well - judge by the rest of the page. |
| Shelf space | depends | OSD Nero Stream XD2 takes up about 60% less shelf area (688cm² against 1701cm²), and it is 110mm shallower, which is the measurement that decides whether a rack door shuts. |
| Price | A | Yamaha A-S301 costs less - $350 against $400 at list. |
A Yamaha A-S301 B OSD Nero Stream XD2
depends neither is better in the abstract - it turns on your room, your system or how you will use them. Only specs published for both amplifiers are judged; anything missing on either side is left out rather than guessed.
Which should you choose?
Yamaha A-S301 has the edge on paper, though not by much. The rows marked "depends" are more likely to decide this than the score is. If your speakers are a difficult load - 4 ohms nominal, big woofers, or a sensitivity in the low 80s - OSD Nero Stream XD2 is the safer partner, because how an amplifier behaves when the impedance drops matters more than its 8-ohm rating. If you play records, Yamaha A-S301 saves you buying a phono stage; if you do not, ignore that row entirely.
What a spec sheet cannot show: how either sounds with your speakers, how the controls feel day to day, and what the app is like to live with - which is where most all-in-one amplifiers are actually won or lost. Power figures are the manufacturers' own and are not measured to a common standard, so treat small differences as noise. If you can hear both, that will tell you more than any row above.