No single best amplifier here. What decides it is what you have to drive, what you need to plug in, and how much of the system you want in one box.
| Area | Better | Why |
|---|
| Built-in DAC | evenly matched | Both have a DAC on board with much the same capability. |
| Phono stage | depends | MISSION 778X has a built-in phono stage (MM) and Marantz M-CR612 does not. Decisive if you own a turntable, completely irrelevant if you do not - and an outboard phono stage is easy to add later either way. |
| Built-in sources | depends | Marantz M-CR612 has a CD player built in. That is one less box if you still play discs or listen to radio, and dead weight if you do not. |
| Amplifier class | depends | Marantz M-CR612 is Class D and MISSION 778X is Class A/B. Class D runs cool and draws almost nothing at idle; Class A/B runs warm and is the long-established mainstream choice. Modern examples of both measure well - judge by the rest of the page. |
| Price | B | MISSION 778X costs less - $549 against $650 at list. |
A Marantz M-CR612 B MISSION 778X
depends neither is better in the abstract - it turns on your room, your system or how you will use them. Only specs published for both amplifiers are judged; anything missing on either side is left out rather than guessed.
Which should you choose?
Neither runs away with it - they trade advantages. Let the "depends" rows and the speakers you already own settle it. If you play records, MISSION 778X saves you buying a phono stage; if you do not, ignore that row entirely.
What a spec sheet cannot show: how either sounds with your speakers, how the controls feel day to day, and what the app is like to live with - which is where most all-in-one amplifiers are actually won or lost. Power figures are the manufacturers' own and are not measured to a common standard, so treat small differences as noise. If you can hear both, that will tell you more than any row above.