There are two main factors that set how easy or difficult a speaker is to drive, these are Speaker Sensitivity and Impedance. A speaker rated lower Ohms requires more current than a higher Ohm speaker. Similarly, a speaker with lower sensitivity requires more power to reach the same volume as a speaker with higher sensitivity.
Wilson Audio Autobiography's nominal impedance level is 4 Ohms but can go down to as low as 2.1 ohms. 8 Ohms is pretty much the standard impedance amongst stereo speakers and amplifiers so Wilson Audio Autobiography is not considered a difficult to drive speaker from Impedance perspective.
Wilson Audio Autobiography has a sensitivity of 89.5 dB.
Read our detailed Wilson Audio Autobiography Review